Saint Joseph's at Villanova 6:30 PM ET
No. 18 Villanova will look to extend its winning streak to five when it hosts Big 5 rival Saint Joseph's on Wednesday.
Northeastern at Seton Hall 6:30 PM ET
After losing consecutive games during its trip to San Diego around Thanksgiving, Seton Hall will look to bounce back on its Newark, N.J., home court Wednesday evening against Northeastern.
Central Michigan at Ohio St. 7:00 PM ET
Ohio State hopes to carry momentum from a championship weekend into its home game against Central Michigan on Wednesday night in Columbus, Ohio.
Buffalo at James Madison 7:00 PM ET
With two true road games, two games at home and two at neutral sites, No. 22 James Madison has not had a November schedule typical of a Top 25 team.
Texas A&M at Virginia 7:15 PM ET
No. 14 Texas A&M looks to continue to build on its resume with another game against a big-time opponent when it travels to play talented Virginia on Wednesday in Charlottesville, Virginia, in an ACC/SEC Challenge game.
Tennessee at North Carolina 7:15 PM ET
Tennessee and North Carolina are eager for a victory when they meet Wednesday in Chapel Hill, N.C., in the inaugural ACC/SEC Challenge.
Florida at Wake Forest 7:15 PM ET
Wake Forest is trying to build momentum before hitting December.
Bellarmine at Louisville 8:00 PM ET
Louisville will try to put together only its second two-game winning streak under second-year head coach Kenny Payne when crosstown Bellarmine University visits the KFC Yum! Center in Louisville, Ky., on Wednesday night.
Merrimack at Georgetown 8:30 PM ET
On paper, Georgetown's rebuild is off to a promising start.
North Florida at Iowa 9:00 PM ET
Ben Krikke has quickly settled in as one of Iowa's best players.
Colorado at Colorado St. 9:00 PM ET
The rivalry between Colorado and No. 20 Colorado State is normally about bragging rights within the state, but there is a little more on the line on Wednesday when they meet in Fort Collins, Colo.
Sam Houston St. at Arizona State 9:00 PM ET
Arizona State, which bounced back from being routed by BYU on Thanksgiving to defeat Vanderbilt the following day in the Vegas Showdown, returns home to face Sam Houston on Wednesday in Tempe, Ariz.
Duke at Arkansas 9:15 PM ET
Duke encountered some unexpected recent glitches but found ways to work through them.
Virginia Tech at Auburn 9:15 PM ET
A fixture in the rankings for five of the last six seasons, Auburn is anxious to return to its familiar perch under Bruce Pearl.
Boston College at Vanderbilt 9:15 PM ET
Vanderbilt and Boston College will look to return to the win column when they meet in the ACC/SEC Challenge on Wednesday night in Nashville.
Georgia at Florida State 9:15 PM ET
Throughout their struggles last season, one thing remained constant for the Florida State Seminoles. They can still win overtime games.
Eastern Washington at Southern California 11:00 PM ET
After splitting a pair of games against high-profile opponents in San Diego last week, Southern California returns home to Los Angeles to host Eastern Washington for a nonconference matchup on Wednesday.